18.8% of mortgage holders are underwater - http://t.co/65FfdhDc3o http://t.co/RTlmf7XGNv
8:25pm May 20th 2014 via Hootsuite
RT @HarvardBiz: Why America Is Losing Its Entrepreneurial Edge http://t.co/2HXJwEnk5U
7:20pm May 20th 2014 via Hootsuite
The Age of Quantum Computing Has (Almost) Arrived | Clive Thompson WIRED http://t.co/zjsm2YzSHY
6:45pm May 20th 2014 via Hootsuite
BBC News - Prostate cancer 'may be a sexually transmitted disease' http://t.co/kmK7vzNTZt
6:20pm May 20th 2014 via Hootsuite
A #LabChat video about the @iontorrent Chef system with an early-access customer | YouTube http://t.co/LDiEsNLBk9
4:20pm May 20th 2014 via Hootsuite
Blekhman: A human geneticist but looking at host-microbiome interactions. Reviewed human genetic variation and microbiome relation #ASM2014
3:05pm May 20th 2014 via Hootsuite
Ran Blekhman (Univ MN): A Role for Host-Bacteria Interactions in Shaping Patterns of Genetic Variation across Human Populations #ASM2014
2:59pm May 20th 2014 via Hootsuite
Jones: Use Nasonia wasps as a genetic model. 4 closely related spp diverged 1MYA. Can get interfertile spp and look at Wolbachia #ASM2014
2:47pm May 20th 2014 via Hootsuite
Jones: Wolbachia is a global pandemic, infects 40% arthropods, 90% of filarial nematodes. Co-evolution of host-microbe interaction #ASM2014
2:46pm May 20th 2014 via Hootsuite
Lisa Funkhouser-Jones (Vanderbilt): Control of Microbial Inheritance: Maternal Suppression of Wolbachia Endosymbiont: Genetic Basis #ASM2014
2:45pm May 20th 2014 via Hootsuite
Poole: V4 of 16S analyzed by QIIME; 25 individuals and 12 timepoints: no profound effect by AMY1 CNV #ASM2014
2:38pm May 20th 2014 via Hootsuite
Poole: From 108 Cornell undergrads, AMY1 CNV assessed by qPCR; assessed oral & gut microbiome. 2w controlled diet #ASM2014
2:36pm May 20th 2014 via Hootsuite
Poole: At low AMY1: microbes have a lot of starch, many SCFA's. High AMY1, lower microbe-produced SCFA's. #ASM2014
2:35pm May 20th 2014 via Hootsuite
Poole: More calories come from host amylase; AMY1 exhibits CNV; shown 1-15 copies. 2007 Perry paper http://t.co/WAqDxSVMgi #ASM2014
2:34pm May 20th 2014 via Hootsuite
Poole: Amylase from saliva, then another shot in the stomach. Glucose gives 2900kJ/mol in host; microbes give short-chain FA's #ASM2014
2:31pm May 20th 2014 via Hootsuite
Angela Poole (Cornell): The Effect of Salivary Amylase Gene Copy Number on Gut Microbiota Composition and Function #ASM2014
2:30pm May 20th 2014 via Hootsuite
.@infoecho It makes me remember how efficient things can be when there are limits (like 48K RAM in an Applie ][)
2:28pm May 20th 2014 via Hootsuite in reply to
Pomp: Pointed out this recent paper in Front Neurol http://t.co/O0Iwj0GAjI connecting GI tract microbiome to Alzheimers #ASM2014
2:23pm May 20th 2014 via Hootsuite
Pomp: Glutamate is an abundant neurotransmitter; host genome affects gut microbes -> Glutamate/GABA -> gut and brain function #ASM2014
2:22pm May 20th 2014 via Hootsuite
Pomp: Overlaid with complete metabolic landscape of the gut microbiome; strongest for glutamate / butyrate metabolism #ASM2014
2:21pm May 20th 2014 via Hootsuite
Pomp: Function by PCA analysis: glutamate & butyrate metabolism. PC1 35% of variation. KEGG pathway analysis #ASM2014
2:20pm May 20th 2014 via Hootsuite
Pomp: Many phenotypes, Benson at U NB-L, looking no longer at 16S but metagenomics. Summary of QTL result: LOD by genomic position #ASM2014
2:18pm May 20th 2014 via Hootsuite
Pomp: Looking at 8-strain outbred mice: distribution of wheel-running (lazy to marathoners); now look at microbiome from these #ASM2014
2:15pm May 20th 2014 via Hootsuite
Pomp: Host predisposition affecting microbiome in the gut? As a mediator - in the case of obesity traits in particular #ASM2014
2:11pm May 20th 2014 via Hootsuite
Pomp: Published in 2010 PNAS http://t.co/REX6oxJfSl Looked at QTL of host genes affecting microbiota #ASM2014
2:10pm May 20th 2014 via Hootsuite
Pomp: Video of activity of mice: 40% of activity level is inherited; looking for host genes affect microbiome #ASM2014
2:08pm May 20th 2014 via Hootsuite
Daniel Pomp (Univ NC Chapel Hill): Genomes, Guts, and Glutamate: A Means for Host-Microbe Interaction? #ASM2014
2:07pm May 20th 2014 via Hootsuite
RT @servingscience: Our own @DaleYuzuki interviewing Drew Kebbel at #ASM2014 ! Stay tuned for the video... http://t.co/aqoahzCiSd
1:32pm May 20th 2014 via Hootsuite
RT @bacteriality: Ok. @geochurch should just run the world. I'm going home. #asm2014
12:20pm May 20th 2014 via Hootsuite
Great to see many #asm2014 attendees at the @iontorrent Profuct Theater workshop! http://t.co/U3VlmtssEQ
12:01pm May 20th 2014 via Hootsuite
RT @profvrr: Great phage t-shirt spotted at #asm2014. http://t.co/ej2Q01xvZD anyone? http://t.co/wkMjmzCHqb
11:25am May 20th 2014 via Hootsuite
Jansson: A lawn: after devastation, weeds will run wild; probiotics, prebiotics, bacteriotherapy Nature 2012 http://t.co/E6NgCoDcVv #ASM2014
10:25am May 20th 2014 via Hootsuite
Jansson: Twin proteomes: showing metabolic pathway differences, from Erickson PLOS 2012 http://t.co/SJeACBguEE #ASM2014
10:11am May 20th 2014 via Hootsuite
Jansson: Showed a 3D video showing the composition changing over time with IBD; some spp changing little, others dramatically so #ASM2014
10:09am May 20th 2014 via Hootsuite
Jansson: IBD: on the rise, Crohn's 0.7%, Ulcerative Colitis 1.5%. Twin cohort: of 46 pairs, 2008 Publ. http://t.co/9Jy1dlRzPU #ASM2014
10:05am May 20th 2014 via Hootsuite
Jansson: Omics: 16S to metagenomics to metatranscriptomics, metaproteome, metametabolome. Current grand challenge is data #ASM2014
10:02am May 20th 2014 via Hootsuite
Jansson: HMP paper referred to 2012 Nature: http://t.co/k4hfdhxjGz What is the function across body sites? What link to health? #ASM2014
10:01am May 20th 2014 via Hootsuite
Jansson: Looking across - from 16S, meagenomes, proteomic, transcriptomic. Mentions the HMP, what 'normal' is from 242 indivs #ASM2014
9:59am May 20th 2014 via Hootsuite
Janet Jansson (Lawrence Berkeley National Lab): “Multi-omics of the human micorbiome - filling in the missing links” #ASM2014
9:58am May 20th 2014 via Hootsuite
Dorrestein:Q: Spatial resolution? A: can push to 10um, for human maps limit is swabbing, multiple cm #ASM2014
9:56am May 20th 2014 via Hootsuite
Dorrestein: (Remarkable datasets from MS combined with NGS metagenomics and human body imaging data.) #ASM2014
9:55am May 20th 2014 via Hootsuite
Dorrestein: Free fatty acid present - tested in culture, oleic and oxidized oleic acids confirming hypothesis #ASM2014
9:54am May 20th 2014 via Hootsuite
Dorrestein: Correlate 850 microbial maps + 50K molecule maps across a surface? A taxon score; illus. with propriobact. and MS data #ASM2014
9:53am May 20th 2014 via Hootsuite
Dorrestein: Found a gut-derived molecule on the bottom of the foot? Crowdsourced. Rob Knight sequenced overlaid to ID spp #ASM2014
9:51am May 20th 2014 via Hootsuite
Dorrestein: Visualized amazing movie of human body model, overlaid with molecules across the surface. Gradients #ASM2014
9:50am May 20th 2014 via Hootsuite
Dorrestein: Illustrating tool with human skin microbiome: sampled MALDI and UPLC-Q TOF from skin #ASM2014
9:49am May 20th 2014 via Hootsuite
Dorrestein: 50-70 searches/day, uploaders, wide variety of organisms. Link to GNPS: http://t.co/zeETeFoPUf #ASM2014
9:46am May 20th 2014 via Hootsuite
Dorrestein: Illustrates 2011 to 2014 dataset and computational growth. "By 2015 we need the NSA's supercomputer" #ASM2014
9:42am May 20th 2014 via Hootsuite
Dorrestein: Requests for using tool; 35pg of instruction. Recent work using their tool 2014 Nature http://t.co/3Hu8YZDLH0 #ASM2014
9:41am May 20th 2014 via Hootsuite
Dorrestein: Can annotate by organism, other attributes "I see a lot of chemistry here" in MS data #ASM2014
9:38am May 20th 2014 via Hootsuite
