MA: Points out high dose IL-2 treatment; effective for only 10%; points out Rosenberg's work for TIL + IL-2 in melanoma #guinformatics
10:49am October 2nd 2014 via Hootsuite
Michael Atkins "Cancer Immunotherapies - A journey from the wilderness to the promised land" #guinformatics
10:47am October 2nd 2014 via Hootsuite
AB:A continuum: from super high-risk, to close to commercializing. #postdocalypse is a hashtag: here's new way to do science #guinformatics
10:28am October 2nd 2014 via Hootsuite
AB:Q:New co's? A:High-risk proj not about co's. Redefined role: "I'm an idea generator" Best grants close to best biz plans #guinformatics
10:27am October 2nd 2014 via Hootsuite
AB:Q:Neurosci? A:Allen Inst., psych is ahead b/c of classification, but behind in others. 'We all have to catch up' #guinformatics
10:25am October 2nd 2014 via Hootsuite
AB: "We need more researchers doing this, using other people's data" "You can't trust that data, need to do it yourself" #guinformatics
10:24am October 2nd 2014 via Hootsuite
(Personal note: read about @atulbutte 's work before, first time hearing him well worth the effort to make it to #guinformatics today.)
10:23am October 2nd 2014 via Hootsuite
AB: #BigData in biomedicine: new drugs for diseases, dx before they occur, amazing platform for entrepreneurship #guinformatics
10:21am October 2nd 2014 via Hootsuite
AB: Showshis own child - 3rd floor of San Jose's Tech Museum, expressing GFP via a 5yo. We've got to get them comfortable #guinformatics
10:20am October 2nd 2014 via Hootsuite
AB: "Maybe kids today need to start 'garage biotechs'" #guinformatics
10:19am October 2nd 2014 via Hootsuite
AB: 'We are used to kids starting...' high-value companies. "I believe the next Amgen will start in a garage." #guinformatics
10:18am October 2nd 2014 via Hootsuite
AB: They are the first to release clinical trial data. The future. http://t.co/skOvYiXTsL #guinformatics
10:17am October 2nd 2014 via Hootsuite
(Now I notice I should be using #guinformatics, oh well!) AB: FDA regulation of mobile apps (200) #biomedical_informatics_symposium
10:16am October 2nd 2014 via Hootsuite
AB: Points out WaPo piece: difference in what hospitals charge for identical procedure. Is it quality? #biomedical_informatics_symposium
10:14am October 2nd 2014 via Hootsuite
AB: Scanadu - the tricorder idea. Indiegogo crowdfunding. $1.6M in a few days #biomedical_informatics_symposium
10:13am October 2nd 2014 via Hootsuite
AB: Theranos has transparent pricing ($3 to $17), 'I have had this done' Patients will get results fast #biomedical_informatics_symposium
10:12am October 2nd 2014 via Hootsuite
AB: Illus. Theranos, disclosed first round was $400M. Make blood testing pleasant, at Walgreens #biomedical_informatics_symposium
10:11am October 2nd 2014 via Hootsuite
AB: Showed graph of weight of himself for 20 mo. Biggest change - his Dr. knows nothing about this #biomedical_informatics_symposium
10:10am October 2nd 2014 via Hootsuite
AB: Now: Withings and fitbit: 5 people have here (~100 attending), on West Coast 'about 1/2'. #biomedical_informatics_symposium
10:09am October 2nd 2014 via Hootsuite
AB: An email from Europe entitled 'I have small cell lung cancer' "Can you help me?" #biomedical_informatics_symposium
10:08am October 2nd 2014 via Hootsuite
AB: Companies license the drug even at 'Phase -1' via computational model; how transl. occurs #biomedical_informatics_symposium
10:07am October 2nd 2014 via Hootsuite
AB: After mouse model, 15mos later a human trial has begun. So NuMedii launched. $3.5M #biomedical_informatics_symposium
10:06am October 2nd 2014 via Hootsuite
AB: Points to anti-depressant paper for small cell lung cancer 2013 PubMed http://t.co/h2OSK6OGay #biomedical_informatics_symposium
10:05am October 2nd 2014 via Hootsuite
AB: Remarkable video showing IBD in rat. 'Built for dry bench researchers' and need to learn exp'l design #biomedical_informatics_symposium
10:04am October 2nd 2014 via Hootsuite
AB: In review, asked for improved photos. A rat colonoscopy (!) video shown. (Outsourced too.) #biomedical_informatics_symposium
10:02am October 2nd 2014 via Hootsuite
AB: Doing duplicate expt, different vendor. First one, IBD using anti-seizure drug in rat model #biomedical_informatics_symposium
10:01am October 2nd 2014 via Hootsuite
AB: Outsourcing flexible - certifications (many options), location etc. Can it be trusted? Diff. vendor #biomedical_informatics_symposium
10:00am October 2nd 2014 via Hootsuite
AB: Effect of price transparency. $9K for 16 mice? 'A goldmine for us'. All computation is tested. #biomedical_informatics_symposium
9:59am October 2nd 2014 via Hootsuite
AB: $9K expt, 9w time, ordered over the internet. Many clearinghouses for CROs or core facilities #biomedical_informatics_symposium
9:58am October 2nd 2014 via Hootsuite
AB: Going to an animal model: outsources to 'Assay Depot', testing a compound in any mouse model offered #biomedical_informatics_symposium
9:57am October 2nd 2014 via Hootsuite
AB: Viagra has been repurposed for lung circulation. 'Let's find new uses on purpose'. #biomedical_informatics_symposium
9:56am October 2nd 2014 via Hootsuite
AB: Refers to 2011 Sci Trans Med paper illus http://t.co/ioezwb96VO new model. Like http://t.co/DJWvZLPR2h #biomedical_informatics_symposium
9:55am October 2nd 2014 via Hootsuite
AB: In 2018, that's $290B lost revenue b/c of the patent cliff. It 'comes down to us' to help solve it #biomedical_informatics_symposium
9:53am October 2nd 2014 via Hootsuite
AB: Shows @matthewherper 2012 Forbes' piece http://t.co/IV3QYwtYcS $4B to $12B real cost. Patent cliff '18 #biomedical_informatics_symposium
9:52am October 2nd 2014 via Hootsuite
AB: A new way to get science done - get to a stage where it can be implemented. 18mo from start to seed $ #biomedical_informatics_symposium
9:50am October 2nd 2014 via Hootsuite
AB: Found a single marker in maternal blood. Carmenta (company) started on this; ended w/ $2M funding #biomedical_informatics_symposium
9:49am October 2nd 2014 via Hootsuite
AB: Pre-eclampsia - personally affected; between OB and Pediatrics. 56 maternal deaths/100K births #biomedical_informatics_symposium
9:48am October 2nd 2014 via Hootsuite
AB: Publication review of kinds of results: cancer markers, transplant rejection, pre-eclampsia #biomedical_informatics_symposium
9:47am October 2nd 2014 via Hootsuite
AB: Same process for pathology samples; shows a tissue microarray. 'we do this like crazy now' #biomedical_informatics_symposium
9:45am October 2nd 2014 via Hootsuite
AB: Illustrates the 'add to shopping cart' idea ordering a sample. Legal use of peripheral blood samples #biomedical_informatics_symposium
9:44am October 2nd 2014 via Hootsuite
Photo of @atulbutte at #biomedical_informatics_symposium http://t.co/nEJk99UJtU showing Affymetix GeneVhips
9:43am October 2nd 2014 via Hootsuite
AB: 'As an MD, we hate RNA as a MDx... but we love proteins' 'ELISAs work in the desert' #biomedical_informatics_symposium
9:40am October 2nd 2014 via Hootsuite
AB: Not only papers, but also the data. Directive from White House. Science piece http://t.co/0M8lqZMmFf #biomedical_informatics_symposium
9:38am October 2nd 2014 via Hootsuite
AB: 'This data is sitting there... waiting for you. And it only gets better.' Sharing papers within 1y #biomedical_informatics_symposium
9:36am October 2nd 2014 via Hootsuite
AB: Calls out PubChem - 127M cmpds x 740k assays. 1.2B data within 100T cells http://t.co/j8resdTTef AB: #biomedical_informatics_symposium
AB: Before Framingham's 14K + 30y of data - hidden. Now 'click to download' 'what an amazing world' #biomedical_informatics_symposium
9:35am October 2nd 2014 via Hootsuite
AB: Points out dbGAP, NIH priority of release, the entire Framingham Heart Study http://t.co/1tijPNNIxO #biomedical_informatics_symposium
9:34am October 2nd 2014 via Hootsuite
AB: TCGA: 20 cancers, 20K samples, RNA, DNA, cyto, 'and they give this stuff away' #biomedical_informatics_symposium
9:33am October 2nd 2014 via Hootsuite
AB: Shows the high-school student who did this: Brittany Wagner, won the GOOG science fair. #biomedical_informatics_symposium
9:32am October 2nd 2014 via Hootsuite
AB: Points out NCBI's GEO database. "Public big data = retroactive crowdsourcing" http://t.co/YUA5r8ypuS #biomedical_informatics_symposium
9:31am October 2nd 2014 via Hootsuite
