Where Will a Biology PhD Take You? Infographic|ASCB http://t.co/qHhoE78lau
6:30am January 12th 2015 via Hootsuite
RT @gedankenstuecke: This day I will now just cry a bit more: A Career in Science Will Cost You Your Firstborn http://t.co/ycXemmAETR
5:05am January 12th 2015 via Hootsuite
How to raise successful children — advice from parents lucky enough to know - The Washington Post http://t.co/ywFZi1QQzt
4:05am January 12th 2015 via Hootsuite
When personalized medicine, genomic research, and privacy collide. | Slate http://t.co/cwBIF9olDd HT @joyclee
3:20am January 12th 2015 via Hootsuite
PLOS Genetics: Modeling 3D Facial Shape from DNA http://t.co/FHL8luTzQn
2:20am January 12th 2015 via Hootsuite
RT @cbschicago: Did you read this story? Cold Snap Making Annual Lull In Blood Donations Worse http://t.co/p74r9ecyV4 http://t.co/YM4DtERqs2
1:50am January 12th 2015 via Hootsuite in reply to
RT @VentureBeat: Genetics testing company Invitae files for an initial public offering http://t.co/CpcJGoPx0Z
12:50am January 12th 2015 via Hootsuite in reply to
RT @joe_palazzolo: “The Snuggery now charges $50 for 45 minutes and $425 for an overnight cuddle session.” http://t.co/MkIde3ywyD
11:05pm January 11th 2015 via Hootsuite in reply to
Improve your conference experience with Twitter | Behind the Bench http://t.co/W5BZBN3mG9 #PAGXXIII
10:50pm January 11th 2015 via Hootsuite
PB: Goals of an open digital framework; short-term training opps; dev. discipline of biomedical data science and cross-training #PAGXXIII
10:04pm January 11th 2015 via Hootsuite
PB: Illus w/songbirds & human - Pfenning et al Science 2014 http://t.co/C2h6cXxXJM as an example of what could be done #PAGXXIII
10:03pm January 11th 2015 via Hootsuite
PB: What is the business model of a commons? A portion of a grant dedicated to IT: awarding credits instead #PAGXXIII
10:00pm January 11th 2015 via Hootsuite
PB: Describes a digital commons - a UID with metadata that is platform agnostic (public cloud, HPC, other platforms) #PAGXXIII
9:58pm January 11th 2015 via Hootsuite
PB: NIH's policy on data sharing: http://t.co/rnc9IJEuyM Also data citation: legitimize data as a form of scholarship #PAGXXIII
9:53pm January 11th 2015 via Hootsuite
PB: Community, Policy & Infrastructure: three elements of the Digital Enterprise. Intersection: sustainability, collab, training #PAGXXI
9:50pm January 11th 2015 via Hootsuite
PB: These problems are shared - BD2K Initiative website: http://t.co/omQuHnBbs6 What's the most efficient way to make data avail? #PAGXXIII
9:49pm January 11th 2015 via Hootsuite
PB: Nor do we have how all the data we have are used. No leverage of an Amazon or Netflix model "you may be interested in..." #PAGXXIII
9:46pm January 11th 2015 via Hootsuite
PB: But - no data sustainability plan in place yet. 'We don't have a 'how' for it' #PAGXXIII
9:44pm January 11th 2015 via Hootsuite
PB: Global communities are emerging - points out Global Alliance for Genomics & Health http://t.co/pSlspNV26L #PAGXXIII
PB: ADDS mission: an open ecosystem to enable research to be conducted 'as a digital enterprise'. http://t.co/xycuyGLklP #PAGXXIII
9:42pm January 11th 2015 via Hootsuite
PB: References 2012 Begley Nature on reproducing studies http://t.co/x0d6v29My6 and how it can affect funding #PAGXXIII
9:40pm January 11th 2015 via Hootsuite
PB: Illus how sol'ns can come from unexpected places - like working with gamers on crowdsourcing. But unintended consequences #PAGXXIII
9:38pm January 11th 2015 via Hootsuite
PB: Evidence is Waze, 3D printers. 'The Story of Meredith' Single-author paper. Unusual 15 y.o. Fora: http://t.co/8q01S1jg5n #PAGXXIII
9:37pm January 11th 2015 via Hootsuite
PB:Showed single CD from 1993 containing NCBI. Today: 40 Petabytes. 'Second machine age' AMZN - http://t.co/jnsLQGSIom #PAGXXIII
9:31pm January 11th 2015 via Hootsuite
PB: From an observational to a more analytical science: driven by inc amts of digital data. "Sociological more than anything" #PAGXXIII
9:30pm January 11th 2015 via Hootsuite
PB: "We're just at the beginning" in this #bigdata era. Finding, Accessing, Integrating, Reusing: 'digital research objects' #PAGXXIII
9:28pm January 11th 2015 via Hootsuite
PB: Computer tapes - shipped to Australia, printed out, then transferred. Now - the proteome of Ebola visualized in seconds #PAGXXIII
9:27pm January 11th 2015 via Hootsuite
PB: What is a digital enterprise? How quickly we've come: maintaining the Protein Data Bank - starting with 15 structures! #PAGXXIII
9:26pm January 11th 2015 via Hootsuite
RT @pebourne: #PAG2015 #PAGXXIII PAG keynote slides - The NIH as a Digital Enterprise: Implications for PAG http://t.co/v86FA2TSw8
9:25pm January 11th 2015 via Twitter Web Client
Philip Bourne (NIH Bethesda Maryland) "NIH as a Digital Enterprise – Implications for PAG" #PAGXXIII @pebourne
9:24pm January 11th 2015 via Hootsuite
RG: SIRE retrotransposons my have accumulated in geographic-specific migration pattern: Indonesia to Mozambique to W Africa #PAGXXIII
8:48pm January 11th 2015 via Hootsuite
RG: Looking at SIRE retrotransposon family across 62 diploit spp - some groups amplified, others completely absent. #PAGXXIII
8:47pm January 11th 2015 via Hootsuite
RG: Sampled 10 diploid Coffea spp; using @rochesequencing at low-pass (6% - 15%), surprised that # of repeats constant #PAGXXIII
8:43pm January 11th 2015 via Hootsuite
RG: 188 Copia and 387 Gypsy LTR retrotransposon families in C canefora. Evidence is recent amplification #PAGXXIII
8:41pm January 11th 2015 via Hootsuite
RG: Tn elements in C canephora is >50%; LTR retroposons are 42% (!) A cut-and-paste mechanism #PAGXXIII
8:40pm January 11th 2015 via Hootsuite
RG: Genome size varies - smallest in E Africa, largest in W Africa. Madagascar: smaller in N, larger in S. Mechanism unk #PAGXXIII
8:39pm January 11th 2015 via Hootsuite
RG: 124 spp world-wide. (Coffea 104, Psilanthus 20 spp) Diverse fruit color, sie, flower morphology #PAGXXIII
8:36pm January 11th 2015 via Hootsuite
Romain Guyot (IRD UMR France) "Transposable Element Distribution, Abundance and Impact in Genome Evolution in the Genus Coffea" #PAGXXIII
8:35pm January 11th 2015 via Hootsuite
AK: Full-length cDNA seq using @pacbio - 4.6k consensus isoforms, ave readlength of isoform 7.5kb P6/C4 chemistry, 2 SMRTcells #PAGXXIII
8:30pm January 11th 2015 via Hootsuite
AK: Looked at 16 microsatellites, 135 Arabica accessions, cultivated ones cluster; wild accessions diverge #PAGXXIII
8:26pm January 11th 2015 via Hootsuite
AK: PacBio gave 9.8k contigs, N50 267Kb. Short reads: 119k contigs, N50 of 8.8kb. Both about 80% est genome size #PAGXXIII
8:23pm January 11th 2015 via Hootsuite
AK: A di-haploid is not tetraploid; C. canephora can create dihaploid 1n=22. Autofertile, but some cross-pollination #PAGXXIII
8:20pm January 11th 2015 via Hootsuite
AK: Shor read, long read (PacBio), GBS, RNA-Seq both short and long reads; high-density maps #PAGXXIII
8:18pm January 11th 2015 via Hootsuite
AK: Showed geographic distribution of canephora across Africa; 7 groups assessed, ancestor of arabica is Ugandan #PAGXXIII
8:17pm January 11th 2015 via Hootsuite
AK: One goal is to catalog diversity of C arabica via GBS and multiple wild and cultivated accessions #PAGXXIII
8:16pm January 11th 2015 via Hootsuite
Alexandre de Kochko (IRD UMR DIADE, Montpellier, France) "Dihaploid Coffea arabica Genome Sequencing and Assembly" #PAGXXIII
8:14pm January 11th 2015 via Hootsuite
MM: Presently they are merging BAC pool assy w/ short-read assy, and then align against canephora seq. #PAGXXIII
8:11pm January 11th 2015 via Hootsuite
MM: Uses 'alignment-free sequence comparison' - groups of kmers canephora- or -eugenioides specific for assigning contigs #PAGXXIII
8:07pm January 11th 2015 via Hootsuite
MM: Showed kmer analysis - large peak unique; secondary peak identical sequences in the tetraploid #PAGXXIII
8:00pm January 11th 2015 via Hootsuite
MM: Overall coverage was 98x w/short reads; 132x from BAC approach. #PAGXXIII
7:57pm January 11th 2015 via Hootsuite
