Preview of tomorrow night - the ongoing fight. #CancerFilm
10:54pm March 31st 2015 via Twitter Web Client
But 'limited success didn't mean ultimate triumph'. Headline - Avastin fails clinical trial... no could imagine twists & turns. #CancerF
10:53pm March 31st 2015 via Twitter Web Client
'Validates 25y search - the beginning of targeted therapy.' All the information we got - is now being used to help people #CancerFilm
10:51pm March 31st 2015 via Twitter Web Client
'There is a description of herceptin and Gleevec as a four-minute mile.' "You break the idea of the limit." #CancerFilm
10:50pm March 31st 2015 via Twitter Web Client
In '98 - given a green-light for CML, and found a 100% response rate 'unheard of'. Rapid, w/o side effects, amazing to see. #CancerFilm
RT @DrStevenLin: "Retroviruses and the #Genetic Origins of #Cancer, 1970-1993" Dr. Varmus http://t.co/ZLaoVlCt64 #CancerFilm http://t.co/5j…
10:48pm March 31st 2015 via Twitter Web Client
Barbara - 'it's an element of fear... a monkey on your back... that never goes away' #CancerFilm
10:47pm March 31st 2015 via Twitter Web Client
'If the data keeps coming back, this is the way to go, you have to believe it'. Barbara "And it's never come back." #CancerFilm
10:46pm March 31st 2015 via Twitter Web Client
'97 trial complete - 'I ran to Art's office and drew the survival curve.' Herceptin - ave 50% increase in lifespan #CancerFilm
'Activism reached a boiling point' - demanding access; 'it just didn't happen w/cancer before'. 1995 - co agreed to lottery #CancerFilm
10:45pm March 31st 2015 via Twitter Web Client
Yet caution is warranted - so many false hopes. Marty Nelson's death in 1994, activists hold funeral at Genentech's campus #CancerFilm
10:44pm March 31st 2015 via Twitter Web Client
RT @jennifermirsky: Navigating treatment options on a patient's own terms. "If I'm going to die, I don't want to die bald and throwing up."…
10:42pm March 31st 2015 via Twitter Web Client
Barbara Bradfield herself - first patient of herceptin (Genentech), news hailed as a 'breakthrough'. #CancerFilm
RT @TeakyW: Watching #CancerFilm and thinking of all the folks in my life touched by cancer. Great book, moving documentary.
10:36pm March 31st 2015 via Twitter Web Client
John Bailar "More are dying of cancer than the year before; how does this match up w/reports of wonderful progress?" #CancerFilm
10:07pm March 31st 2015 via Twitter Web Client
"There was deep chasm between the lab and the clinic that no one could bridge" 1986: "Progress against cancer?" #CancerFilm
10:06pm March 31st 2015 via Twitter Web Client
Wilson: "Being an oncologist, this is who I am." 'You know how the story will end.' #CancerFilm
10:05pm March 31st 2015 via Twitter Web Client
Hard to see Dr. Lori Wilson, w/double mastectomy. Risk coming back is 50%. (Hearing their stories in their own words is hard.) #CancerFilm
10:04pm March 31st 2015 via Twitter Web Client
'We have not slain our enemy, the cancer cell. We have only seen our monster more clearly.' Varmus #CancerFilm
10:01pm March 31st 2015 via Twitter Web Client
The first oncogene, ras, was discovered by Weinberg. 'First time there was a mechanistic explanation. A total revolution.' #CancerFilm
10:00pm March 31st 2015 via Twitter Web Client
From 10's of thousands of genes, how to find the cancer-causing gene? Sprinkling genes one at a time, to find the one. #CancerFilm
9:59pm March 31st 2015 via Twitter Web Client
"If you turn up enough stones, you'll find something." (Weinberg caught in a Boston snowstorm, walking out of a cave of shadows) #CancerFilm
9:58pm March 31st 2015 via Twitter Web Client
Late '70's - a worldwide hunt for the human oncogene. 'Science is a profession for manic/depressives' (Weinberg) #CancerFilm
9:57pm March 31st 2015 via Twitter Web Client
'Now a glimpse of cancer's cause' - genes for growth, a single explanation 'the oncogene'. It won Varmus/Bishop the Nobel. #CancerFilm
9:56pm March 31st 2015 via Twitter Web Client
Ducks, emus, 'and by fiddling with the technology, we 'found it in humans'. Genes causing cancer 'already in animal genomes' #CancerFilm
9:55pm March 31st 2015 via Twitter Web Client
src almost superfluous - why is there? Orig. in the chicken? "It was a riveting moment" (Bishop) to find it in chicken. #CancerFilm
9:54pm March 31st 2015 via Twitter Web Client
RSV has only 4 genes. Simplified problem 'immensely'. gag, pol, env, src. What is src? Extra gene causes gene 'oncogene' #CancerFilm
9:53pm March 31st 2015 via Twitter Web Client
Molecular biology was developing; instruments to peer inside the cells (thanks @appliedbio!) and find mechanism of disease #CancerFilm
9:52pm March 31st 2015 via Twitter Web Client
Harold Varmus 'I studied English Lit more than science'; Bishop worked with him, studied Rous Sarcoma Virus (RSV). #CancerFilm
9:51pm March 31st 2015 via Twitter Web Client
Ames: genes being mutated >was< the relationship between viruses and chemicals. A grand unified theory of cancer. #CancerFilm
9:50pm March 31st 2015 via Twitter Web Client
1967 - Bruce Ames made a 'momentous discovery'; 'we ought to have an easy test to see if they are mutagens'. #CancerFilm
9:49pm March 31st 2015 via Twitter Web Client
'Cancer is a disease of the genome goes back to the beginning of the 20th century' (Lander) #CancerFilm
9:48pm March 31st 2015 via Twitter Web Client
What do viruses and chemicals have in common? Could it be genes? There were clues... 'largely ignored' (Bishop) #CancerFilm
9:47pm March 31st 2015 via Twitter Web Client
"And to solve it, we need to solve the most difficult problem of all - the nature of life itself" #CancerFilm
9:46pm March 31st 2015 via Twitter Web Client
RT @CancerCenter: Smoking causes lung cancer and so much more. #CancerFilm http://t.co/L3AjKsnCr0
RT @sloan_kettering: Today, tobacco use causes 87% of lung cancer deaths in men and 70% in women, via @AmericanCancer #CancerFilm http://t.…
9:42pm March 31st 2015 via Twitter Web Client
Pair of studies came to the same concl.; cigarette co's said 'complex and still obscure' 'other factors' 'keep an open mind' #CancerFilm
9:41pm March 31st 2015 via Twitter Web Client
RT @ACSLubbock: By 1945 lung cancer comprised 20% of all cancers. #CancerFilm
9:40pm March 31st 2015 via Twitter Web Client
Hill and Dahl asked 100's of Q's - and 1 Q on smoking. And only one link to cancer - cigarettes. #CancerFilm
9:38pm March 31st 2015 via Twitter Web Client
But viruses not the singular cause. Then: a chemical one. 1775 - Percival Pott noticed scrotal cancer in chimney sweeps #CancerFilm
9:35pm March 31st 2015 via Twitter Web Client
RT @TCGAupdates: Check out the Rous paper on "Sarcoma of the Common Fowl" http://t.co/N4lCebE365 #Cancerfilm #openaccess
9:33pm March 31st 2015 via Twitter Web Client
Epstein-Barr virus first one linked to human cancer. Terrifying to public, and cancer vaccine worked on in early '70's #CancerFilm
9:32pm March 31st 2015 via Twitter Web Client
Harold Varmus (@theNCI) - hard to push experiments past the Rous experiments. Abdominal tumors in Africa, Burkitt's #CancerFilm
9:31pm March 31st 2015 via Twitter Web Client
1908: Payton Rous, tested by a LI chicken tumor. ID'd as a virus. 1 pg paper 'and all hell broke loose' (Bishop narrates) #CancerFilm
9:29pm March 31st 2015 via Twitter Web Client
Long believed: a single cause and a single cure. But disagreed onto the cause: Viruses. Chemicals. Genes. All silo-ed. #CancerFilm
9:27pm March 31st 2015 via Twitter Web Client
A Howard Univ MD Laurie Wilson diagnosed with cancer herself; two different types; one TNBC :( Hard to watch. #CancerFilm
9:24pm March 31st 2015 via Twitter Web Client
Fisher overthrew central dogma "cutting more meant curing more"; treatment w/o understanding mechanism causes damage #CancerFilm
9:19pm March 31st 2015 via Twitter Web Client
1985: the results released. 'No significant difference' - whether you 'amputated the whole breast' or not, 'it was the same' #CancerFilm
9:18pm March 31st 2015 via Twitter Web Client
Yet patients themselves (the women) found out there was an alternative. Science journalist Rose Kushner to the rescue. #CancerFilm
9:17pm March 31st 2015 via Twitter Web Client
He was tough: "In God we trust; all others must bring data". Thought to be a traitor. Denied funding, couldn't recruit pts #CancerFilm
9:16pm March 31st 2015 via Twitter Web Client
