RT @AllSeq: Advances in NGS – free online conference from SelectBio will have a special focus on RNA sequencing http://t.co/xJw6aEjotU
9:20am March 20th 2015 via Hootsuite in reply to AllSeq
RT @tomstafford: How a grad student's 3am blog comment became a paper (currently being presented with a Nobel laureate as discussant) http:…
9:03am March 20th 2015 via Twitter Web Client
RT @moorejh: Our search for new biomedical #informatics faculty at @penn, @PennMedicine has launched https://t.co/7v3e0Xg0VU #bioinformatics
8:20am March 20th 2015 via Hootsuite in reply to moorejh
RT @rowgirl2012: "10 Physician-Authored Blogs Worth Reading" http://t.co/Oyb5hOVa0M…
7:10am March 20th 2015 via Hootsuite
If you are looking for a solid web host, @asmallorange has been great. Now w/ a 40% discount do check it out. http://t.co/eeZKV5yFpm
6:05am March 20th 2015 via Hootsuite
RT @DailyNewsGW: ESHG, ASHG include 10 recommendations in joint statement on NIPT in clinical practice. http://t.co/skm1vm5XWb
5:00am March 20th 2015 via Hootsuite
RT @Ginkgoo: Now you know what an organism engineering foundry looks like - meet Bioworks1! http://t.co/Z3fHKyHk7l… http://t.co/VoAvB4g4ra
4:25am March 20th 2015 via Hootsuite
MT @PistoiaAlliance: Our Interactive Genome Analysis Challenge featured on @DNADigest http://t.co/1zxnHOJDxz http://t.co/EyuirV4Wvs
10:40pm March 19th 2015 via Hootsuite
MT @omicsomicsblog: @KrzysztofMKozak optical mapping's reign in scaffolding will be short; variety of seq methods already nipping at heels
9:55pm March 19th 2015 via Hootsuite
RT @SOBRNetwork: Fantastic advice for PhD Students! Tips From Professors, Startup Founders, and Industry Professionals. #phdchat http://t.c…
9:41pm March 19th 2015 via Twitter Web Client
.@splon Great to see often unrecognized heroism be recognized, esp. the lab tech's clear understanding of the consequences of their work.
9:32pm March 19th 2015 via Hootsuite in reply to splon
Lab technician braves blizzard for results that save newborn's life WCVB Boston http://t.co/pr1KGXDx71
8:55pm March 19th 2015 via Hootsuite
iGenomics at iTunes Appstore from @mike_shatz http://t.co/jIJAhWG3W1 Tutorial: http://t.co/7Z9ICDt3xk HT @omicsomicsblog
7:35pm March 19th 2015 via Hootsuite
RT @NIAAAnews: Dr. Koob talks about efforts to reduce college drinking with @NPR http://t.co/JH7nFlNqiB http://t.co/PL8JmfeGWC
6:08pm March 19th 2015 via Twitter Web Client
RT @Bob_Wachter: .@EricTopol on #Apple's #ResearchKit http://t.co/QV1F4EGIwh "May be most important advance in history of clinical research"
6:05pm March 19th 2015 via Hootsuite
A Single-Cell Breakthrough | Bioscience Technology http://t.co/jS5pI0wfAN
5:20pm March 19th 2015 via Hootsuite
RT @michaelhoffman: CM: assay DNA mutation, 5hmC, 5mC, RNA, RNA 5mC, proteomics, antibody, chromatin state, others on twins before/during/a…
5:19pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM on Twins study. Scott Kelly on ISS for one year. Mark Kelly monozygotic twin on earth.
RT @michaelhoffman: CM playing with @nanopore MinION. Getting up to 71 kbp reads. Will send one into the space station. Only sequencer you …
RT @michaelhoffman: CM quoted in @Gothamist article entitled "'Licking Subway Poles "Probably Fine,' Says Expert" http://t.co/OgpGjSZre4
4:52pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: PathoMAP available on http://t.co/66sEE64BT9 See which subway stations are have kimchi- or pizza-associated bacteri…
RT @michaelhoffman: CM: 36% of small molecules in your blood are from the microbiome.
4:42pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM introduces the "epiproteome" to mean post-translational modifications. (Used 2x in PubMed)
RT @michaelhoffman: CM: There are many RNA modifications, including m6A. Enriched at 3' ends of genes. http://t.co/uGfxgpK8Wb
RT @michaelhoffman: CM: single-cell RNA-seq reveals extraordinary heterogeneity. Fluidigm C1, $50/cell.
4:41pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: Global epigenetic change of tumor can e larger w/in one patient in 6 months than between strangers.
RT @michaelhoffman: CM: You can use epialleles as a barcode to reveal clonality http://t.co/IJK1sV3Nl6 https://t.co/Amz4WEI2q1
4:40pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: Polymorphic epiallele detection can be highly variable. "Epipolymorphism" http://t.co/2eOUpyKbt1
RT @michaelhoffman: CM: Epigenetic age ("methyl-age") accelerated in most cancers. Mean is 36 years.
RT @michaelhoffman: .@mason_lab at Princess Margaret Cancer Centre: "Genome profiling for single cells, entire cities, and the internationa…
.@notSoJunkDNA @michaelhoffman @mason_lab I've done it before - not an easy task!
4:39pm March 19th 2015 via Twitter Web Client in reply to notSoJunkDNA
RT @RobertCGreen: Less is more! An entire whole genome sequence summarized in a ONE page report for primary care docs http://t.co/X4G9uaWObw
4:15pm March 19th 2015 via Hootsuite
MT @noamross and @MozillaScience AMA: organizing local groups to teach + learn research coding: 3/24, 3PM PST http://t.co/DtkraHf6fH
3:10pm March 19th 2015 via Hootsuite
GW: Hypomethylation of FKBP5 is intron/CpG-specific, dose-dependent in brain and blood. Pattern similar for both stress and anxiety #NIAAA
2:41pm March 19th 2015 via Hootsuite
GW: One recent ref about FKBP5: http://t.co/cfRv93qlWJ Is a co-chaperone w/GC receptor. Higher FKBP5, higher serum cortisol #NIAAA
2:35pm March 19th 2015 via Hootsuite
GW:FKBP5 gene studied in detail: ass'd with risk alleles for PTSD, stress-induced cortisol levels, suicide #NIAAA
2:33pm March 19th 2015 via Hootsuite
GW: Networks: circadian, scaffolding, Wnt, even DISC1, FOXP1. >1000 DMRs had ID CpG betw. blood and brain DNAs #NIAAA
2:32pm March 19th 2015 via Hootsuite
GW: Promoters, islands, shores, DNAse-sensitive sites; confirmed via Pyrosequencing. Found 5K DMRs, GC favored loss of methylation #NIAAA
2:31pm March 19th 2015 via Hootsuite
GW: Now onto cytosine methylation by cortisol. C57BL/6J mice; Agilent genome-wide Methyl-Seq capture looking for DMRs induced by GC #NIAAA
2:29pm March 19th 2015 via Hootsuite
GW: Familial component for Alcohol Use Disorders can be 4x to 10x in families with history of abuse #NIAAA
2:00pm March 19th 2015 via Hootsuite
GW: Alcoholics have dysregulation; also have a stress-dampening period that can last for months in abstinence #NIAAA
1:53pm March 19th 2015 via Hootsuite
GW: Glucocorticoids can feedback negatively under stress 1971 http://t.co/gx8PJZGvlT Alcoholics produce high cortisol in withdrawal #NIAAA
1:52pm March 19th 2015 via Hootsuite
GW: His focus on glucocorticoid component of stress response. Hypothalamus down to pituitary, to adrenal via HPA axis. #NIAAA
1:48pm March 19th 2015 via Hootsuite
GW: Becker Ref: http://t.co/yIUtWeAaAi Stress (stimulus), allostasis (compensatory response), allostatic shift (chronic stress) #NIAAA
1:46pm March 19th 2015 via Hootsuite
Am attending @niaaanews talk, 'Cortisol dysregulation and alcoholism: consequence, correlation or causality' by Gary Wand (Hopkins) #NIAAA
1:42pm March 19th 2015 via Hootsuite
RT @NIAAAnews: "Cortisol Dysregulation and Alcoholism: Consequence, Correlation or Causality," Dr. Gary Wand @1:30, videocast link: http://…
1:41pm March 19th 2015 via Twitter Web Client
RT @ldtimmerman: Content creators need copyright protection, like drug developers need patent protection.
12:05pm March 19th 2015 via Hootsuite
ZW: Conclude: the splicing code is not straightforward (like the genetic code), rather 'like the IRS tax code' - interdependent #NHLBI
12:00pm March 19th 2015 via Hootsuite
ZW: Finding relatively poor overlap between periodic gene expression and periodic splicing. Evidence that AS 'tunes coding potential' #NHLBI
11:55am March 19th 2015 via Hootsuite
ZW: Looking at cell-cycle dependence - very deep RNA-Seq (150M/sample). Finding 'widespread periodic alt-splicing' #NHLBI
11:52am March 19th 2015 via Hootsuite
