Switzerland will vote on having a national wage of £1,700 a month | The Independent https://t.co/jdCpL3mNiQ
8:28am January 31st 2016 via Hootsuite
Zika: The Unexpected Pandemic | Medpage Today https://t.co/iGbWjmyvXk
10:10pm January 29th 2016 via Hootsuite
Modern Grief: digital ephemera and coping with loss · thewalrus.ca https://t.co/23wscNBG3i
9:32pm January 29th 2016 via Hootsuite
Machines Won’t Become Dangerously Smart Anytime Soon | Technology Review https://t.co/1LclEXSQY8
7:50pm January 29th 2016 via Hootsuite
RT @DrKhouryCDC: "I just found out I have the BRCA gene mutation and...I don't know what to do." Via @marieclaire https://t.co/lrxhCscDz5
6:05pm January 29th 2016 via Hootsuite
In praise of artificial food — Aeon https://t.co/J2WJEAzGHa
5:45pm January 29th 2016 via Hootsuite
Time Entanglement Raises Quantum Mysteries | Quanta Magazine https://t.co/gtmzAWi0vD
4:45pm January 29th 2016 via Hootsuite
Oliver: Detection done on-the-fly; 8mm square piece of silicon. Shows an hourglass-shaped schematic of the fluidic channel #GIAB
1:02pm January 29th 2016 via Hootsuite
John Oliver (Nabsys 2.0): Small-molecule electronic mapping, sub-diffraction-limit resolution; DNA moves at 1MB/sec (!) #GIAB
12:58pm January 29th 2016 via Hootsuite
Hickey: 9K dels, 12K ins, 2.5K "other" novel variants (24K) from 1 sample (!) #GIAB
12:54pm January 29th 2016 via Hootsuite
Hickey: They are now working on the Ashkenazim Trio as a de novo project. Working with Sebra (Mt Sinai Icahn SOM). N50's at 4-5MB #GIAB
12:53pm January 29th 2016 via Hootsuite
Hickey: Reviews progress of their 'Platinum Genomes' CHM de novo assemblies using hyatidiform mole human haploid lines #GIAB
12:52pm January 29th 2016 via Hootsuite
.@TorontoGenomics Online streaming here for #GIAB (if you are interested): https://t.co/m1pCSK53PS
12:51pm January 29th 2016 via Hootsuite in reply to TorontoGenomics
Hickey: They have white papers for >30kb library inserts. Now onto WGS with NA12878 #GIAB '15 Nature Methods https://t.co/lW4dlLJ0eH
12:49pm January 29th 2016 via Hootsuite
Hickey: Shows data from PFGE - ave about 40kb; but compared to longer E coli DNA input, longer reads (15kb vs 11kb) achieved #GIAB
12:42pm January 29th 2016 via Hootsuite
Hickey: P6-C4 gives 10K-15Kbp. Uses RM8398, they use to help dev novel library prep. Dependence of DNA quality and length of data #GIAB
12:40pm January 29th 2016 via Hootsuite
Hickey: Since C2 3y ago: throughput increased by 100x. Enzymology, chemsitry, SMRTcells, and the instrument. #GIAB
12:38pm January 29th 2016 via Hootsuite
Hickey: SEQUEL announced at ASHG, 1M ZMWs at 1/2 the price. Data analyses where public access has been a benefit to them #GIAB
12:37pm January 29th 2016 via Hootsuite
Hickey: Library mentions G2 Covaris, Sage Pippen prep as key developments for them. SMRTbell now uses human genomes as ref material #GIAB
12:36pm January 29th 2016 via Hootsuite
Hickey: >10kb read-lengths, 99.999% acc at 30x. Divides development into 3 parts - library, sequencing, data #GIAB
12:35pm January 29th 2016 via Hootsuite
RT @westr: More evidence for broad-range NGS (IMHO): 'A Cancer Legacy' @sciencemagazine https://t.co/NFIIPzgxIn #PM101 https://t.co/7AIqYxD…
12:34pm January 29th 2016 via Twitter Web Client
Luke Hickey (PacBio) #GIAB Starts with a plea for quality reference material, for development and validation processes. Reviews SMRT tech
12:33pm January 29th 2016 via Hootsuite
Q: Will the BAM files be shared from #GIAB data? A: A balance - as info could be used by their competitors.
12:31pm January 29th 2016 via Hootsuite
10X Genomics: Using competitive long-read technology as well as extended pedigree for haplotype inh to validate this approach. #GIAB
12:28pm January 29th 2016 via Hootsuite
10X Genomics: Works with Seraphim Batzoglou's group at Stanford to dev this approach; increase SNP sens. Interested in how to validate #GIAB
12:27pm January 29th 2016 via Hootsuite
10X Genomics: Lariat: a Linked-Read aligner - repetitive or paralogous regions with barcodes now can use flaking unique regions to map #GIAB
12:26pm January 29th 2016 via Hootsuite
10X Genomics: In the context of haplotype - "many interesting things that can be done in that context." #GIAB
12:25pm January 29th 2016 via Hootsuite
10X Genomics: Using phase data to check SV detection: Showing a 1.2kb deletion, color by haplotype, very clear loss by haplotype #GIAB
12:24pm January 29th 2016 via Hootsuite
10X Genomics: Able to distinguish between three cell types by RNA profiling. 'Already selling this'. Public released NA12878 data #GIAB
12:23pm January 29th 2016 via Hootsuite
10X Genomics: Shows photo of a T-cell inside a droplet; barcoding individual transcripts (like Cellular Research). Shows low doublets #GIAB
12:21pm January 29th 2016 via Hootsuite
#GIAB Showing N50 phase block of 30MB; w/add'l patitions are going to de-novo assembly. Going to single cell now: partitioning cells.
12:19pm January 29th 2016 via Hootsuite
Now 10X has gone to >1M partitions; improved biochemistry for uniform coverage; is compatible to HiSeq 10X. #GIAB
12:17pm January 29th 2016 via Hootsuite
At #GIAB first-up is 10X Genomics and how they've used GIAB material. "Chromium Genome" project (prelude to more info at #AGBT16)
12:15pm January 29th 2016 via Hootsuite
Givers, Takers and Matchers - an analysis of workplace relationships - YouTube https://t.co/pzsUgXSf1S
9:45am January 29th 2016 via Hootsuite
RT @kirkenglehardt: A new data journalism tool – and a new way of reporting uncertainty. https://t.co/84iHEzIOKF @paulbradshaw #scicomm
8:31am January 29th 2016 via Hootsuite
RT @iontorrent: NCI Pediatric MATCH Trial Takes Shape; Study Expected to Open This Year - https://t.co/6zGGKt5QFq
7:35am January 29th 2016 via Hootsuite
My Generic Side: becoming a stock photography model · thewalrus.ca https://t.co/3nDsvbMdU0
7:30am January 29th 2016 via Hootsuite
This is how much money you’re worth to Facebook - The Washington Post https://t.co/FfpEC561Vp https://t.co/NLVR7rph4Y
6:45am January 29th 2016 via Hootsuite
RT @matthewherper: Theranos’s main retail partner, Walgreens, is suspending some ties to the blood-testing lab https://t.co/XkKnXY0zKh
5:40am January 29th 2016 via Hootsuite
RT @iontorrent: 1 week left until the PGS webinar on Feb 3! Register now to learn how to detect aneuploidy using NGS https://t.co/LQGRTkR69q
4:40am January 29th 2016 via Hootsuite
RT @splon: These are the links to all three papers published today on childhood cancer genomics https://t.co/IjFYu2JmOb
3:35am January 29th 2016 via Hootsuite
RT @AMPath: Barbara Zehnbauer's editorial in @JMDiagn #precisionmedicine Online now at: https://t.co/S41VyP6XLs https://t.co/WgjLkrY0vm
10:25pm January 28th 2016 via Hootsuite
RT @JSTORPlants: Examining how much biodiversity we no longer consume: https://t.co/R3TkZDrL1w https://t.co/uqUN5ohd80
9:25pm January 28th 2016 via Hootsuite
RT @DrKhouryCDC: Ethical & societal issues in using gene editing in practice. @JAMA_current https://t.co/bvmCHSh4II https://t.co/SmDfCMH
8:25pm January 28th 2016 via Hootsuite
RT @claritas4kids: #GIAB16 DY: test assay to assay and lot to lot consistency, allele frequency intended to be ~20%, usually +/- 3%
6:26pm January 28th 2016 via Twitter Web Client
RT @claritas4kids: #GIAB16 DY: solid tumor mutation mix includes RET, MPL, BRAF, KRAS, TP53, FLT3, PIK3CA (2) plus
RT @claritas4kids: #GIAB16 DY: cardiomyopathy panel with varying allele frequencies, 10 deleterious mutations in 10 genes, add to AJ son fo…
RT @claritas4kids: #GIAB16 Dale Yuzuki from SeraCare talking about Seraseq tools for NGS, solid tumor mutation mix, ctDNA reference, aneupl…
Swift Biosciences and SeraCare Partner on Circulating Tumor DNA | PR Newswire https://t.co/cQL5Si001y
6:08pm January 28th 2016 via Hootsuite
Lincoln: "Fit for purpose" for germline is 'easy'. FDA's method-based validation - need tricky types. Q:which way will labs go? #GIAB
5:25pm January 28th 2016 via Hootsuite
