Buck: 'Healthy' definition depends. A minor impact is the host genome; major impact is the environment. #BHCRForum17
1:33pm April 19th 2017 via Hootsuite
A healthy microbiome in the vaginal tract? Buck: Sampling does matter, lactobacillus. W/6K women, 60% AfAm, different profile #BHCRForum17
1:31pm April 19th 2017 via Hootsuite
Buck: Correlative science is very difficult to determine causative agent (Koch's postulates) Focus now on mechanism, function #BHCRForum17
1:24pm April 19th 2017 via Hootsuite
Ravel: Stool re-implantation done many years ago post-surgery. Then forbidden, now done via FMT #BHCRForum17
1:21pm April 19th 2017 via Hootsuite
Ravel: The 'hygiene hypothesis' where an environment was too clean; children developing autoimmunity this environment. #BHCRForum17
1:19pm April 19th 2017 via Hootsuite
Riscuta: Acidity of the stomach changes w/age; involvement w/inflammation, other diseases of aging. #BHCRForum17
Suzich: Who cares? What may it be resp for? Riscuta:Bacteria, fungi, viruses; first obs w/Bulgarians, longer lived w/diet #BHCRForum17
1:17pm April 19th 2017 via Hootsuite
Buck: Equated to seeing the back-side of the moon: prior techniques limited what we could see. #BHCRForum17
1:14pm April 19th 2017 via Hootsuite
Buck: NGS has brought to light 'microbial dark matter' due lack of ability to culture. NGS in '06: can study w/o culturing #BHCRForum17
1:13pm April 19th 2017 via Hootsuite
Suzich: Enabling technologies beyond culture? Ravel: From the 1800's, by cultivation. Genomic revolution has made it possible. #BHCRForum17
1:11pm April 19th 2017 via Hootsuite
Buck: 100x-genes w/microbes cp to human genes everyone has. Called a 'second genome'. Negative things as well as positive. #BHCRForum17
1:10pm April 19th 2017 via Hootsuite
Buck: Microbiome a very impt topic: about 2-3lbs of microbes in and around humans, not by accident, they have co-evolved w/us #BHCRForum17
1:08pm April 19th 2017 via Hootsuite
JoAnn Suzich (VP MedImmune) Greg Buck (VCU) Jaques Ravel (UMD) Gabriela Riscuta (NCI) #BHCRForum17
1:07pm April 19th 2017 via Hootsuite
Advancing science: We are not alone: Understanding the microbiome in health and disease #BHCRForum17
Marcus: We go to where the best scientific and commercialization paths exist #BHCRForum17
11:55am April 19th 2017 via Hootsuite
Marcus: Third Rock, Arch may do their own deal. Grail $900M largest Series A ever; fewer but larger deals. Policy can make diff #BHCRForum17
11:54am April 19th 2017 via Hootsuite
Alexandria is a top VC; what is your criteria? Marcus: #4 most active; Arch is #1. $500M on balance sheet; agnostic to location #BHCRForum17
11:53am April 19th 2017 via Hootsuite
Marcus: The VCs are now in Cambridge, now woefully lacking here. Delaney: They 'don't want to fly to their board mtgs' #BHCRForum17
11:52am April 19th 2017 via Hootsuite
Austin: HGS, founded by ex-NIH, Harvard, decided to found it in Rockville. 'What are the chances of that happening today?' #BHCRForum17
11:51am April 19th 2017 via Hootsuite
Delaney: Feels we in MD are 'punching way below our weight; we don't get / earned our fair share of venture capital' #BHCRForum17
11:50am April 19th 2017 via Hootsuite
Delaney: "Here we celebrate public policy." In early '80s Bayh-Dole legislation: how transformative it was w/incentives. #BHCRForum17
11:49am April 19th 2017 via Hootsuite
Delaney: The incentives really matter, and the culture matters. Celebrating business success, for example, in CA #BHCRForum17
11:48am April 19th 2017 via Hootsuite
What about UMD C-P? Austin: Refers to the LSAB and UMD system; but it is 15 campuses, how to connect them all? #BHCRForum17
11:46am April 19th 2017 via Hootsuite
Austin: Hopkins is the #1 recipient of NIH; but not an entreprenuerial culture. Building out an innovation park #BHCRForum17
11:42am April 19th 2017 via Hootsuite
Austin: How to get connectivity? How to liberate the incredible science already here but not in the marketplace? #BHCRForum17
11:41am April 19th 2017 via Hootsuite
Austin: Cambridge, Mission Bay, RTP. Then "Maryland, for those who do not know, is a state" #BHCRForum17
Marcus: Vs biopharma - the opposite, where collaboration is key. Delaney: Stealing things in tech is common, short timeframe #BHCRForum17
11:40am April 19th 2017 via Hootsuite
Delaney: The ROI could be huge. Marcus: Negotiating of a top tech co; Apple, Google, Amazon: require no competitors in tech #BHCRForum17
11:39am April 19th 2017 via Hootsuite
Delaney: What about Cornell setting up engineering in Roosevelt Is? What about a campus in DC? 'Better than another stadium' #BHCRForum17
11:38am April 19th 2017 via Hootsuite
Delaney: Issues with traffic; acad inst but don't orient toward sciences. Hopkins a treasure, but pretty 'darn far'. #BHCRForum17
11:37am April 19th 2017 via Hootsuite
Delaney: MA, CA, NY: All high taxes and heavily regulated, but it's 'where everyone wants to be'. Very high quality of life. #BHCRForum17
Marcus: Where is that location in the MD region? Baltimore? I-270? Not concentrated enough. #BHCRForum17
11:34am April 19th 2017 via Hootsuite
Marcus: Shady Grove could be the same; but missing the UCSF, the MIT, the Stanford. UCSF: valuing spinouts at 7th GDP worldwide #BHCRForum17
11:33am April 19th 2017 via Hootsuite
Marcus: Same thing in SF with Mission Bay, NYC on the East River; all of which have same factors - millenials, fitness, retail #BHCRForum17
11:32am April 19th 2017 via Hootsuite
Why a focus on physical space? Marcus: A big bet in '04, 1M sf in Cambridge, upzoned to 2M sf w/retail, conference, companies #BHCRForum17
11:31am April 19th 2017 via Hootsuite
Austin: $2B of NIH monies stays in MD; there's a total of $3.5B spent in MD. NCATS does no basic research. #BHCRForum17
11:27am April 19th 2017 via Hootsuite
Austin: NIH is a federation; no central place like at a company. NCATS serves as an entry-point, focused on translation #BHCRForum17
11:21am April 19th 2017 via Hootsuite
Greenwood: Not obvious how to avail of great research from NIH? Austin: "I work in John's district and work in Joel's building" #BHCRForum17
11:20am April 19th 2017 via Hootsuite
Marcus:You need great management talent, and risk capital. This area 'severely undercapitalized'. #BHCRForum17
11:19am April 19th 2017 via Hootsuite
Marcus: You need a world-class location. FL $1B in Orlando, Boca Raton, St Lucie - closing down. #BHCRForum17
11:18am April 19th 2017 via Hootsuite
Greenwood: What will it take to make a world-class hub? Marcus: 10y in NY, 25y in Boston, these are long-term plays #BHCRForum17
11:17am April 19th 2017 via Hootsuite
Greenwood: Why do the insurers get away with charging so much for co-pays? #BHCRForum17
11:16am April 19th 2017 via Hootsuite
Marcus: And why not the role of PBMs pushing pricing up, to make more on the margin? Publicity in the wrong places #BHCRForum17
11:13am April 19th 2017 via Hootsuite
Greenwood: Generics were very far away from innovation (Epipen example). Marcus: Why the focus on 15% of the healthcare cost? #BHCRForum17
11:12am April 19th 2017 via Hootsuite
Delaney: Genomics projects' promise is 'extraordinary' #BHCRForum17
11:10am April 19th 2017 via Hootsuite
Delaney: Epipen controversy: some areas to discuss but need to be very careful about regulation and investment concerns #BHCRForum17
Delaney: Already much gov't involvement. Pharma prices: knows returns on capital and concerns. There will be debate, discussion #BHCRForum17
11:09am April 19th 2017 via Hootsuite
Greenwood: Concern about gov't intervention in markets? Delaney: Gov't makes large investments in science, technology #BHCRForum17
11:06am April 19th 2017 via Hootsuite
Roundtable: John Delaney (US rep MD 6th dist) Former CEO. Chris Austin (Dir NCATS) Joel Marcus (CEO Alexandria Real Estate) #BHCRForum17
11:05am April 19th 2017 via Hootsuite
Greenwood: Text to 52886 '4bio' to sign up to https://t.co/Fvar9M6PKs - easy! #BHCRForum17
11:00am April 19th 2017 via Hootsuite
