Q: Why only 50% for GIST? Haviland #worldcdx A way to act on testing is impt. Access and other issues (awareness in comm. oncol settings)
8:45am September 11th 2019 via Twitter Web App
Q: How have you chosen CDx tech? Haviland #worldcdx Quality, TAT, Global footprint.
Haviland #worldcdx Only ~50% of GIST patients get molecular testing; they want to change the paradigm. In <10y: 2 approved Rx, many in de
8:43am September 11th 2019 via Twitter Web App
Haviland #worldcdx Tumor-agnostic approach: As varied as RET fusions in papillary thyroid, panc ca, bile duct carcinoma.
8:40am September 11th 2019 via Twitter Web App
Haviland #worldcdx Clin example: real-time monitoring in EGFR-mutant NSCCL and acquired RET fusion, treated w/Tagrisso and pralsetinib.
8:39am September 11th 2019 via Twitter Web App
Haviland #worldcdx Thus KIT-driven Ph III precision medicine trial for their compound in 2L GIST with liquid biopsy excl criteria
8:37am September 11th 2019 via Twitter Web App
Haviland #worldcdx For KIT-driven GIST, used liquid biposy to understand emerging clin data. KIT V654A/T670I (non-responders for GIST)
Haviland #worldcdx Showed expanding results in adv systemic mastocytosis to the smoldering form w/Avapritinib (still in dev)
8:35am September 11th 2019 via Twitter Web App
Haviland #worldcdx Adv systemic mastocytosis, and adv GIST: KIT D816V and PDGFRA D842V - two homol mutant kinases, w/same inhibitor
8:33am September 11th 2019 via Twitter Web App
Haviland #worldcdx And then to use their platform to adapt to tumor evolution. Then expanding the pt popul'n.
8:31am September 11th 2019 via Twitter Web App
Haviland #worldcdx A cycle: detect, interpret, act. Lays out Blueprint's approach: durable selective inhibitors, bi… https://t.co/3ZMKitY3qa
8:30am September 11th 2019 via Twitter Web App
Haviland #worldcdx Recognizes that progress with cancer optimism is fleeting, due to the dynamic nature of cancer.
8:27am September 11th 2019 via Twitter Web App
Haviland #worldcdx Starts with a note: will remember 9/11 in a moment of silence. And remember how long we've come… https://t.co/CoZHdHzXIP
8:26am September 11th 2019 via Twitter Web App
Kate Haviland (Blueprint Medicines) A Virtuous Cycle of Medical Innovation Fueling Advances in Precision Oncology #worldcdx
8:25am September 11th 2019 via Twitter Web App
Salzman #worldcdx Pursuit for precision medicine - 'biomarkers the currency for drug development'.
8:22am September 11th 2019 via Twitter Web App
Chair's opening remarks - Rachel Salzman (SwanBio Therapeutics) The goal: the right drug at the right time to the right patient. #worldcdx
8:20am September 11th 2019 via Twitter Web App
Today at @WorldCDx and will be live-tweeting. Not sure who else will be? #worldcdx https://t.co/iK95NTmL4b
8:14am September 11th 2019 via Twitter for iPhone
Israel #dsdc Bots that can talk to each other. 'A lot of metrics in social is BS.' The ability to gut-check the data.
3:35pm September 5th 2019 via Twitter Web App
Israel #dsdc In '18: 100's of millions of profiles deleted. 'Up to a third of their profiles were fake.' A follower factory isn't illegal.
3:29pm September 5th 2019 via Twitter Web App
Israel #dsdc Before the purge: bot farms that could rig YouTube to get 'popular of the day'. Money for buying 5K Insta followers.
3:27pm September 5th 2019 via Twitter Web App
Israel #dsdc Social isn't even 20 years old. Going back to 2002: Friendster and Myspace. Individuals creating their own brands
3:24pm September 5th 2019 via Twitter Web App
Chad Israel (Siegal Entertainment) #dsdc Measuring Social in Today’s Shifting Sands
3:22pm September 5th 2019 via Twitter Web App
Riding #dsdc Engagement: When people understand their role, know their role matters, and are proud of it.
3:08pm September 5th 2019 via Twitter Web App
Riding #dsdc Velocity of the work? Frequency? Quality? Perception of quality within the org? And satifaction with the work produced?
3:07pm September 5th 2019 via Twitter Web App
Riding #dsdc "Measure what matters." Get stuff 'Done right" - CEO of workfront (Alex Shootman). How much maintenanc… https://t.co/8YQqznJh5G
3:06pm September 5th 2019 via Twitter Web App
Riding #dsdc 60% of marketers go through 5 or more rounds of review. Merry-go-round: it wasn't that good a plan up-front.
2:59pm September 5th 2019 via Twitter Web App
Riding #dsdc Leaders: come with an objective, and takeaways. Make meetings count! It can be for just some 'magical human contact'.
2:55pm September 5th 2019 via Twitter Web App
Riding #dsdc Make collaboration easier. Create an intake process that works for you. Where requests come in, where… https://t.co/UMOcNcW2N6
2:52pm September 5th 2019 via Twitter Web App
Riding #dsdc 40% of our time is what we were hired to do. Is it process or lack of process that kills creativity?
2:48pm September 5th 2019 via Twitter Web App
Riding #dsdc Juggling chainsaws, bombs and scorpions. If we make small changes in the how, it'll make a big difference in the what.
2:46pm September 5th 2019 via Twitter Web App
Riding #dsdc Martech Landscape infographic is larger than ever. https://t.co/pF8m04SvFl
2:44pm September 5th 2019 via Twitter Web App
Mike Riding (Workfront) #dsdc Modernize Your Marketing Work: 4 Simple Ways to Get More Done
2:43pm September 5th 2019 via Twitter Web App
Fisher #dsdc Have opened up a store to sell capes near cost at $3.99; some districts order thousands. Stories - created a comic book.
2:20pm September 5th 2019 via Twitter Web App
Fisher #dsdc The lesson: luck. 'There's hard work after luck.' #redcapenation was something people could participate in.
2:12pm September 5th 2019 via Twitter Web App
Fisher #dsdc The red cape idea at an educator's conference; didn't expect the idea to spread, agreeing with a vision of superhero status.
2:10pm September 5th 2019 via Twitter Web App
Fisher #dsdc Share this teacher testimonial on how the Istation helped a student go from 0 to a 50. https://t.co/cAoeyQZlkT
2:07pm September 5th 2019 via Twitter Web App
Fisher #dsdc The marketing conundrum: student software. Shares Secret Equation Man video https://t.co/XIYmAxS8Ix
2:05pm September 5th 2019 via Twitter Web App
Fisher #dsdc Imagination Station - an edtech company. But literacy is super-important: strong correlation to achievement. And prisons.
2:03pm September 5th 2019 via Twitter Web App
Fisher #dsdc Turning ordinary into extraordinary campaigns; unpack the psychological triggers; and dev a social playbook.
2:01pm September 5th 2019 via Twitter Web App
Ossa Fisher (Istation) #dsdc Contagious Content: Turn Your Customers From Privately Placid to Publicly Passionate
1:59pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Without quality information, propaganda will proliferate. We need to take some resp for our understanding of civics.
1:44pm September 5th 2019 via Twitter Web App
Plumeri #dsdc PG&E, the fires, and the work exposing the money trail: the work of journalists. Facebook.
1:43pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Showed a FB video that tripled their metric for signups. "See where the money leads."
1:40pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Different video audiences - the taster, the snacker, the full meal people. 'The more you say the less they recall.'
1:38pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Optimization - high contrast, fast pacing, large font. Media strategy: Paid, owned, earned, and the goals for each.
1:34pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Shows the 'stipple' drawing (of their faces) and are figuring out how to animate them.
1:31pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Due to time-pressure: have brought meida in-house. Spend distribution 'heavily calibrated to content marketing'.
1:27pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Content - you think of what your customers need, and creating that link and bond.
1:25pm September 5th 2019 via Twitter Web App
Plumeri #dsdc All good journalism starts with a good story. 'It must balance what readers know they want with what… https://t.co/5CTPmxmpzC
1:24pm September 5th 2019 via Twitter Web App
Plumeri #dsdc Had to dig into the journalism itself. Conventionally - order. The news: chaos. 'You can't get used to anything.'
1:23pm September 5th 2019 via Twitter Web App