RT @mkt_sentiment: The most profound advice on the purpose of life is from the most unlikely source as well! https://t.co/eeTCpLzRhf
8:26am April 30th 2023 via Twitter Web App
RT @OlinkProteomics: Join representatives from @uk_biobank, Janssen, Biogen, Olink, Weill Cornell Medicine - Qatar & DNAnexus to walk th
9:47am April 21st 2023 via Twitter Web App
Kummar #AACR23 New Moderna personalized vaccine for combo I-O therapy. A first neoantigen vaccine, unique and large… https://t.co/4gqAzmGvgH
1:04pm April 19th 2023 via Twitter for iPhone
Shivaani Kummar (OHSU Knight CC OR) #AACR23 Clinical research and clinical trials. Themes: Immunotherapy, targeting… https://t.co/btAy8kAfi8
12:58pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 The National Cance Plan was just released. https://t.co/BzyBUtushU
12:55pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 Prostate cancer and genetic testing. High risk variant versus high PRS. https://t.co/mY8NvG4Dhs
12:53pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 “Prevention is better than early intervention is better than treating metastatic disease” David Carbo… https://t.co/53db6ES28I
12:52pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 Aspirin as an intervention, and personalizing it. https://t.co/c7ygD0bc7q
12:50pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 looking at CHIP and clinal mosaicism in normal individuals. https://t.co/3ld6Idc0UT
Platz #AACR23 Omics - PRS has predictive capacity for Prostate Cancer, looking into metabolomics. https://t.co/hzwmJkgTvI
12:48pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 African genetic ancestry can affect treatment response. Also immune, methylation and microbiome diffe… https://t.co/trZwpeVU5G
12:44pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 Personalizing medication after smoking cessation. https://t.co/jAcxvgJjzz
12:39pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 intervening for tobacco use: Ask / Advise / Connect. n=12k. https://t.co/1vIEDp4yJZ
12:38pm April 19th 2023 via Twitter for iPhone
Platz #AACR23 Population health behavioral nudges - better care for cancer patients. “This is science - behavioral… https://t.co/VurE3EWqLU
12:37pm April 19th 2023 via Twitter for iPhone
Elizabeth Platz (John’s Hopkins MD) #AACR23 Prevention, early detection, population sciences, and disparities resea… https://t.co/Xa5YLNQSn6
12:32pm April 19th 2023 via Twitter for iPhone
Stewart #AACR23 Microbiome; Stress: releases neutrophils and increases metasis. Cachexia- and sex differences. Loc… https://t.co/PwwuRorK7i
12:28pm April 19th 2023 via Twitter for iPhone
Stewart #AACR23 Age-related changes and Immunotherapy. Not only age but sex. And ethnic difference as well. Obesity… https://t.co/pNh8Vzbzyo
12:26pm April 19th 2023 via Twitter for iPhone
Stewart #AACR23 Arg is missing in the TME; affecting content of Retinoic acid; dendritic cell populations. https://t.co/YeTZIRxmzQ
12:23pm April 19th 2023 via Twitter for iPhone
Stewart #AACR23 Therapies follows discoveries; personalized Rx requires a holistic view. The 30 year overnight sens… https://t.co/3kU4mANXT8
12:19pm April 19th 2023 via Twitter for iPhone
Sheila Stewart (WashU MO) #AACR23 Basic cancer science and translational research. Nice overview of the Plenary I,… https://t.co/ziL7aNFykw
12:14pm April 19th 2023 via Twitter for iPhone
Highlights of #AACR23 - a vision for the future. R Vonderheide’s introductory remark: “Look around you - you are st… https://t.co/pvwT2IekHJ
12:09pm April 19th 2023 via Twitter for iPhone
Lim #AACR23 Able to look at EMT status, and depletion of WBC. Shows data relating cluster formation to drug respons… https://t.co/nhJ6l6MVAv
11:07am April 19th 2023 via Twitter for iPhone
Lim #AACR23 expanding CTCs to PDX, PDOs, CTC culture: for screening drugs for sensitivity / resistance. Another dev… https://t.co/JKjQEhpCRa
11:03am April 19th 2023 via Twitter for iPhone
Lim #AACR23 Downstream, multiple workflows (types of cell analyses). Another device - for single cell capture and r… https://t.co/YFmzituTSK
11:01am April 19th 2023 via Twitter for iPhone
Lim #AACR23 Third chip is SMART chip, fourth is Spiral Internal Focusing Chip. Looks like a density, differential s… https://t.co/Cvg98URxwU
10:57am April 19th 2023 via Twitter for iPhone
Lim #AACR23 Chips for: cell margination, microfiltration, two others. Will highlight two: Filtration - cell traps.… https://t.co/MtT4wxdB5l
10:55am April 19th 2023 via Twitter for iPhone
Lim #AACR23 CTC isolation - makes a good case. DNA, RNA, proteins of high quality; WGS, cell proteins, functional i… https://t.co/m807Cm8bV2
10:52am April 19th 2023 via Twitter for iPhone
Session: Technical Advances in Liquid Biopsy and Rare Event Detection. Chwee Teck Lim (National Univ Singapore)… https://t.co/EhvbWPZBZT
10:50am April 19th 2023 via Twitter for iPhone
Bowman #AAaVR23 Shows figure of simulations confirmed experimentally. New company called Decrypt Bio. https://t.co/gLWw8KrnzG
9:11am April 19th 2023 via Twitter for iPhone
Bowman #AACR23 ‘23 Nature Comm ref https://t.co/p8dOJk6HPa Online resource https://t.co/8A8sdIA96n
9:10am April 19th 2023 via Twitter for iPhone
Bowman #AACR23 Shows reasonable IC50 for inhibition. Compute is $$, what if we can predict a cryptic pocket from a… https://t.co/OpzBHQgoCv
9:07am April 19th 2023 via Twitter for iPhone
Bowman #AACR23 Mentions https://t.co/qY5H6qVk5g to map protein dynamics. NB - I found the video he showed on YouTub… https://t.co/DnrDLd5L8O
9:04am April 19th 2023 via Twitter for iPhone
Bowman #AACR23 Shows a nice video, illustrating cryptic pockets afford an opportunity 2004 ref… https://t.co/SC6iqTtzv9
8:59am April 19th 2023 via Twitter for iPhone
Greg Bowman (U Penn) #AACR23 What if all your favorite proteins are druggable? Only 15% of proteins are considered druggable per the NCI.
8:56am April 19th 2023 via Twitter for iPhone
Kaskinski #AACR23 Have not used enhancing agents yet - some future direction. 19 ref https://t.co/vc4ImLTI6W
8:54am April 19th 2023 via Twitter for iPhone
Kasinski #AACR23 Shows whole animal images of down-regulation 24 to 120 hr post-injection; marked downreg. 24-48h a… https://t.co/QsgAlgV8W2
8:51am April 19th 2023 via Twitter for iPhone
RT @OncoAlert: The #OncoAlertTopTweet
8:48am April 19th 2023 via Twitter for iPhone
Kasinski #AACR23 Onto modifications on the ribose, and the backbone (phosphorothioate). Shows “do not post” data of… https://t.co/PFyZJN3VDA
8:47am April 19th 2023 via Twitter for iPhone
Kasinski #AACR23 They use a folate-conjugated to miRNA payload from Target Therapeutics. Called FolamiR 2017 Scienc… https://t.co/WzhqkabAp4
8:41am April 19th 2023 via Twitter for iPhone
Kasinski #AACR23 A combinatorial approach 2015 ref https://t.co/nsRHkpnegk Shows illustration on ligand-merited, ve… https://t.co/Tl7jSIhMvd
8:36am April 19th 2023 via Twitter for iPhone
Andre Kasinski (Purdue Univ IN) #AACR23 To the tumor and beyond - tales of a holistic mRNA delivery vehicle. 2013 f… https://t.co/e6UQQNBzIZ
8:33am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 Mice full of Myeloid Derived Suppressor cells (MDSC’s) - a good pro-tumor model. Shows treatment an… https://t.co/Uj5hocdUbR
8:28am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 Use it for a TLR9 agonist; elicit Amit-tumor immunity via targeted immunostimulant therapy, ‘22 ref… https://t.co/rPTlajEwvw
8:25am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 A “bonding site barrier” - increasing dosage of Ab-drug combo improves efficacy, but too high to be… https://t.co/97haJwvTv2
8:23am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 a toolbox of drug conjugates- there’s an optimal range of protein / peptide - kDa in 10-100 is more… https://t.co/fEk2xjZchq
8:20am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 Afemt from the seeds of a “squirting cucumber”. Binds trypsin called EETI-II 2009 Cancer Res 2009 https://t.co/7tR8I9gWkN
8:17am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 Now - why not peptide-drug conjugates? Faster clearance, smaller proteins could penetrate tumors better.
8:15am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 Fc fusions proteins are current blockbuster drugs, over 100 in development. https://t.co/0lmvVeZK1k
8:14am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 1st gen molecule in 2014 https://t.co/xQ2f8X9Sx5 2nd gen is 2017 JCI version. Shows chart of # of m… https://t.co/IMSzswoUbz
8:13am April 19th 2023 via Twitter for iPhone
Cochran #AACR23 An engineered Axl “receptor decoy” - that looks a lot like an Ab - but a molecule that is in clinic… https://t.co/MSiD68kGue
8:10am April 19th 2023 via Twitter for iPhone
