Cheng: #ASHG22 Has samples from 2009, and 2019 measured breast, panc and prostate cancers. Used cfMeDIP-Seq. Shows… https://t.co/cFxMPgTbve
2:27pm October 26th 2022 via Twitter Web App
Cheng: #ASHG22 Developed ML model, problem is most blood is collected at time of Dx. Need to look in asymptomatic i… https://t.co/XygR2x1nAN
2:23pm October 26th 2022 via Twitter Web App
Cheng: #ASGH22 Global and focal changes in cancer methylomes occur early in tumor evolution; can be years before Dx… https://t.co/UJyM8IKs9e
2:21pm October 26th 2022 via Twitter Web App
Nicholas Cheng (Univ Toronto and Princess Margaret MC Canada) #ASHG22 Profiling pre-diagnosis plasma cell-free DNA… https://t.co/1BFc38DNAL
2:20pm October 26th 2022 via Twitter Web App
RT @OlinkProteomics: At this afternoon's 3:00pm-4:45 Poster Session #ASHG22, be sure to check out @taylorlawley's poster PB3176 - Using an…
2:17pm October 26th 2022 via Twitter Web App
Averting Alzheimer's as soon as possible Session at #ASHG22 Ben James (MIT/Broad) looks at snRNA and snATAC to caus… https://t.co/1dfSiLilVv
1:57pm October 26th 2022 via Twitter Web App
Craig: Took Germaine hets and ID spatial LOH, “spatially-driven aneuploidy”. Tool called tLOH, looked at ratios, co… https://t.co/MTBixRp1Ic
1:24pm October 26th 2022 via Twitter for iPhone
Craig: #ASHG22 Glioma has poor prognosis; heterogeneous mixture of cell types, area of hemorrhage, abnormal regions… https://t.co/4hAEiCNMSm
1:18pm October 26th 2022 via Twitter for iPhone
Craig: #ashg22 tSNE and UMAP images going into spatial data - unsupervised data shows overlapping spots. Not at sc… https://t.co/kONSnCBcq3
1:15pm October 26th 2022 via Twitter for iPhone
Cool to hear David Craig (Translational Genomics at USC / Keck) looking at spatial transcriptomics and genomics in… https://t.co/CvmwFFzdjA
1:11pm October 26th 2022 via Twitter for iPhone
Q: #ASHG22 Analytical workflow from Dr. Truong, could multiple cluster analysis be tried? Truong: Not automated; fe… https://t.co/6G01FiE51A
11:06am October 26th 2022 via Twitter Web App
Horvath: #ASHG22 50% of mouse transcripts changed between 1pm and 3pm (!) in brain. "People underestimate the noise in mRNA data"
11:03am October 26th 2022 via Twitter Web App
Q: Non-spec aging in different people - leverage other kinds of clocks - does methylation capture it? Horvath… https://t.co/Yn4QZyV27C
Q: Measuring imputation of methylation vs genotypes? Horvath: #ASGH22 feels it is much more correlated than genotyp… https://t.co/qJ4VQYsPZD
11:00am October 26th 2022 via Twitter Web App
Q&A: Cross-species methylation clock? Horvath: here a presentation at #ASHG22 a 'universal mammalian clock'. High c… https://t.co/A6AlY9
10:58am October 26th 2022 via Twitter Web App
Great speaker lineup for the #ASHG22 @uk_biobank panel discussion. Alas not enough time to address questions! https://t.co/VaW8zyOWwQ
10:52am October 26th 2022 via Twitter for iPhone
Pancholi: #ASGH22 Platform credit programs: 1000GBP 'getting started credit', $500K/year for early career researche… https://t.co/wl99oHouWH
10:50am October 26th 2022 via Twitter Web App
Dr. Mahesh Pancholi (CIO UKB) #ASGH22 Analysing data in the UKB Research Analysis Platform (RAP). 25 petabytes of d… https://t.co/m1HEv4pFvN
10:48am October 26th 2022 via Twitter Web App
Dr. Mahesh Pancholi (CIO UKB) Analysing data in the UKB Research Analysis Platform (RAP). 25 petabytes of data ("al… https://t.co/xjWuUzjFMc
10:44am October 26th 2022 via Twitter Web App
Horvath: #ASHG22 Concl: "we need to carefully choose the measuring platform"; also sample type (blood and/or saliva).
10:43am October 26th 2022 via Twitter Web App
Horvath: #ASHG22 Cost a limitation of using the Illumina Methylation array; 'perhaps a smaller array would allow im… https://t.co/ndtSmORvLJ
10:42am October 26th 2022 via Twitter Web App
Dr. Steve Horvath (Altos Inst of Science) The case for methylation studies #ASHG22 An aspiration for methylation da… https://t.co/oTsoxGDjBE
10:38am October 26th 2022 via Twitter Web App
Cule: #ASHG22 Iron in the spleen in 40K from UKB, previously unstudied, GWAS implicates genes - see poster PB1268
10:35am October 26th 2022 via Twitter Web App
Cule: #ASHG22 Take adv of ML and precision phenotyping, and use genetic variation as a 'natural experiment' to char… https://t.co/pmYrjenmlK
10:34am October 26th 2022 via Twitter Web App
Dr. Madeleine Cule (Calico Labs) #ASHG22 "Precision phenotyping w/abdominal MRI in UKB" Calico: understand biology… https://t.co/idvQYlAh3W
10:31am October 26th 2022 via Twitter Web App
Truong: #ASHG22 Shows interesting Manhattan plot, replicated known signals for MDD, ID'd 6 new genomic regions, pur… https://t.co/TS5m5SyGcC
10:28am October 26th 2022 via Twitter Web App
Truong: #ASHG22 Clustered along top 50 features; genetic assoc'n; now reporting array (genotyping) data. 8 unique p… https://t.co/TPU3sh2gpx
10:26am October 26th 2022 via Twitter Web App
Dr. Dongnhu Truong (Janssen R&D) (Missed the title - about molecular psychiatry - MDD) MDD = major depressive disor… https://t.co/v7vKVD
10:25am October 26th 2022 via Twitter Web App
Black: #ASGH22 Points to data from this '22 review. https://t.co/itjjIZuLdg Concludes: genetic support, predict adv… https://t.co/an4vnI8R5I
10:23am October 26th 2022 via Twitter Web App
Black: #ASHG22 "a resource for accel innovation in early biotech" - 64% of 21 FDA approved druges were by early bio… https://t.co/Wk5xk6RBOL
10:22am October 26th 2022 via Twitter Web App
Black: #ASHG22 Last use-case - examine pt stratification (Predict benefit of evolocumab Rx in pts with artheroscler… https://t.co/55PerUbpwf
10:21am October 26th 2022 via Twitter Web App
Black: #ASHG22 Lists use-cases, one to ID novel drug targets (INHBE gene for obesity), predict target-assoc'd liabi… https://t.co/Jqt8ATESq7
10:19am October 26th 2022 via Twitter Web App
Mary Helen Black (Foresite) Leveraging UKB to enable precision medicine. Emphasize: its uniqueness, open-access pol… https://t.co/lNHarSIG2f
10:17am October 26th 2022 via Twitter Web App
7am Session: How the UK Biobank is enabling scientific discoveries in population health. Short presentations / Pane… https://t.co/J7fZAbhsFH
10:16am October 26th 2022 via Twitter Web App
Smith Gives a great rundown of advances from CE seq and microarray, through OGM and need for SV analyses. They are… https://t.co/ACP0jYBC4T
8:29pm October 25th 2022 via Twitter for iPhone
Smith: Shows a figure of a number of SVS not found via conventional cytogenetics ‘20 ref https://t.co/Szy0UpJfGS #ashg22
8:28pm October 25th 2022 via Twitter for iPhone
Adam Smith (Univ Toronto) How genome mapping technologies will change clinical cytogenetics practice. ELN AML Dx cl… https://t.co/mMBmkTiqmI
8:26pm October 25th 2022 via Twitter for iPhone
Kanagal-Shamanna 50% of SV’s not detected by conventional karyotyping, changed their clinical score. OGM “easy to i… https://t.co/SzYNuhVZ87
8:23pm October 25th 2022 via Twitter for iPhone
Rashmi Kanagal-Shamanna (MD Andersen Tx) Combining OGM w/targeted NGS in hematological malignancies. Shows a few ex… https://t.co/dm12kyo6ot
8:12pm October 25th 2022 via Twitter for iPhone
El-Khattabi: Shows 85/85 for 3 repeat expansion loci types by OGM. Interesting fig of technology coverage and SV si… https://t.co/iW0Tby2stW
8:03pm October 25th 2022 via Twitter for iPhone
El-Khattabi: Now talking about testing male infertility finding balanced translocations in 10/11 pts. ‘20 ref… https://t.co/63ngSrTkVI
8:00pm October 25th 2022 via Twitter for iPhone
Listening to talks in the “Enabling next-generation cytogenetics”, with Laila El-Khattabi (Paris) presenting severa… https://t.co/JmggD8Xjo3
7:56pm October 25th 2022 via Twitter for iPhone
RT @cgonzagaj: CR: Investigated global ancestry of ~6k modern humans from around
4:42pm October 25th 2022 via Hootsuite Inc.
Charles Rotimi, ASHG President, giving the opening address at #ASHG22 “One human race: Billions of genomes” https://t.co/8k1fhYxUdo
4:18pm October 25th 2022 via Twitter for iPhone
Anyone headed over to #ASHG22 should take a look at this remarkable flyer of where the UKB-PPP data will be showcas… https://t.co/4Ch1AgLEbR
12:27pm October 25th 2022 via Twitter Web App
RT @girlscientist: Friends only let friends use #ASHG22
11:55am October 25th 2022 via Twitter Web App
RT @RexChapman: 128 performers in wheelchairs. French choreographer Sadek Waff leads a mesmerising hand ballet during the 2020 Tokyo Para…
11:41am October 25th 2022 via Twitter Web App
Ever wonder what a side-by-side comparison between Olink Explore and an aptamer-based method looks like? Just in ti… https://t.co/pPwDPr0jN6
5:19am October 25th 2022 via Twitter Web App
RT @OlinkProteomics: Olink® Insight now provides customers with an open-access online platform to share knowledge, with multiple tools to s…
8:47am October 24th 2022 via Twitter Web App
RT @kellybarnhill: I have one of the neighbor kids over at my house at present, working on his college essay. I've been doing this a lot la…
11:51am October 17th 2022 via Twitter for iPhone
