Dale Yuzuki

Dale Yuzuki has spent more than twenty-five years in the life science tools industry, spanning genomics, proteomics, and molecular diagnostics. He writes occasionally at yuzuki.org.

A handheld single-molecule diagnostic platform Two Pore Guys

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One of the long-held goals for molecular testing of any sort (from testing the food supply for food-borne illness, to livestock health, to forensic testing, to testing for infectious disease, to screening for cancer) is to obtain inexpensive results without a lot of expensive equipment. The latest effort at ‘point-of-care’ testing has been to take … Read more

NanoString’s Hyb & Seq single-molecule sequencing platform at AGBT 2017

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Last year at Advances in Genome Technology and Biology, NanoString’s Joe Beechem presented their proof-of-concept work around a new single-molecule sequencing technology that had fulfilled a long-lived goal going back many years: sequencing by hybridization. (By the way, if you are interested here’s a 1994 paper by Lee Hood and Rade Drmanac describing this approach via … Read more

Advances in genomic clinical applications

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Genomic medicine will occur when research becomes translated into clinical and reduced to practice. Years ago Eric Green, the Director of the National Human Genome Research Institute (and one of the two organizers of the Advances in Genome Biology and Technology conference) would often talk about the need to make the knowledge of the human … Read more

Advances in Genome Technology

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Many times the fun of AGBT is the advances in genome technology If you have attended Advances in Genome Biology and Technology in the past, sometimes there is amazing technology presented in a plenary session. Who can forget Stephen Turner’s electrifying talk in 2009’s meeting, complete with fireworks on the beach? <https://www.genomeweb.com/blog/fireworks-beach-guess-theyre-officially-out-stealth-mode> (And if you … Read more

BGISEQ-500 Debuts at the International Congress of Genomics 10

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The International Congress of Genomics 10 is a conference held annually in Shenzhen, China where BGI is headquartered. Largely attended by life science researchers in China, the invited speakers will have a natural connection to the genetics and genomics community in China, in particular Huanming Yuan. And over the past seven or eight years BGI … Read more

New Cepheid GeneXpert Omni at #AACC2015

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With my recent transition to the clinical market segment with SeraCare, their major  conference for the year is the American Association for Clinical Chemistry. With some 20,000 attendees, and several hundred vendors filling the Atlanta Convention Center, there were a number of interesting real-time instruments shown. I’ll start with the most impressive and surprising of … Read more

SeraCare Precision Oncology

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Seracare precision medicine ngs control reference material seraseq mutation mix
The Seraseq Solid Tumor Mutation Mix-I (AF20), the first product from SeraCare’s Precision Medicine Group

This post is about Seracare’s new direction for Precision Medicine (in particular Precision Oncology), and the launch of a new product the Seraseq Solid Tumor Mutation Mix-I (AF20). But I’ll start first with a story from my days at Illumina.

It was ten years ago this week that I last launched a product. It was the Illumina Infinium Human-1 Genotyping BeadChip, and it took months of hard work, many core-team meetings, plenty of long days and many hallway discussions about the finest details of the product. Long days and many meetings go together: how can you get the things you commit to in a meeting ever done if you go to many meetings?

And in case anyone is wondering, yes that is the job of a Product Manager – you get to work hard and work closely with a team from across different areas of the company (research, manufacturing, quality, support, and engineering) and you get to experience many ups-and-downs, and learn things about yourself and others through this experience that you carry with you. These may be hard days, but they are good ones.

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